Is BBQ GFCF? Texas Study on Diet and Autism

Gluten_free_tagBy Kim Stagliano

GFCF diet is getting attention and research at UT’s Health Science Center at Houston, Texas. I’m happy to see the study underway, since without proof on paper by scientists at a university, pediatricians will continue to turn around during the exam and roll their eyes when we mention the diet. Just as they did to parents who swore by the Feingold Diet before a study illustrating the adverse effects of artificial colors and flavors on behaviors proved what Mom and Dad had known for years. To its credit, the AAP did put out a statement about the success of the Feinfold diet for some children. It’s a shame American kids aren’t put onto this diet as a matter of course and “prescription” from a doctor (the only way many parents will try the diet) before ADHD drugs.

I have a couple of questions about this GFCF diet study.

1) Who is funding this study? 2) Why only four weeks long? Many of us did not see changes within this short time period. 3) How do they plan to ensure that there is no “cheating?” Will they give the families all of their food for the four weeks? It’s very hard to ferret out all sources of gluten and casein when you’re new to the diet and even as a veteran. 4) Who is funding this study? (Yes, I realize that one repeats.)

(HealthNewsDigest.com)- HOUSTON — Researchers at The University of Texas Health Science Center at Houston have embarked on one of the first double-blind, clinical studies to determine whether gluten and dairy products play a role in autistic behavior as parents have anecdotally claimed.

The pilot study is one of seven current studies on autism in the Department of Pediatrics and the Department of Psychiatry and Behavioral Sciences at The University of Texas Medical School at Houston.

“There’s a lot of misinformation, so that’s why this study is so important,” said Fernando Navarro, M.D., assistant professor of pediatrics at the medical school and lead investigator of the study. “Hundreds and hundreds of parents think this works but we need serious evidence.”

Read the full article HERE.

Kim Stagliano is Managing Editor of Age of Autism. She just ate two pieces of birthday cake. One she baked for her husband’s birthday, loaded with gluten and casein. The other she baked for her children, GFCF. Which tasted better? Only her hairdresser knows… (and if you’re too young to get that line, my apologies. Google it.)

Source: Autism News

Diet And Autism Research Focuses On Which Foods May Affect Autistic Behavior

Researchers at The University of Texas Health Science Center at Houston have embarked on one of the first double-blind, clinical studies to determine whether gluten and dairy products play a role in autistic behavior as parents have anecdotally claimed.The pilot study is one of seven current studies on autism in the Department of Pediatrics and the Department of Psychiatry and Behavioral Sciences at The University of Texas Medical School at Houston.

“There’s a lot of misinformation, so that’s why this study is so important,” said Fernando Navarro, M.D., assistant professor of pediatrics at the medical school and lead investigator of the study. “Hundreds and hundreds of parents think this works but we need serious evidence.”

Autism is a complex neurobehavioral disorder linked to early abnormalities of brain development. According to the National Institute of Neurological Disorders and Stroke, it affects up to six of every 1,000 children and is characterized by impaired social interaction, problems with verbal and nonverbal communication and unusual, repetitive or severely limited activities and interests.

Researchers have discovered that there are differences in the central nervous system’s anatomy and function in those diagnosed with autism, but the cause of the disorder is unknown. Experts theorize it may be a combination of genetics and environment.

“A lot of children with autism have gastrointestinal problems such as constipation and diarrhea. Whether these problems are related to brain development is open to question,” said Katherine Loveland, Ph.D., co-investigator and professor of psychiatry and behavioral sciences, pediatrics and biomedical sciences at the health science center. “There are neurotransmitters and neuroreceptors in the gut that correspond with those in the brain. There are some scientific reasons to think that some kids may benefit from this diet.”

For the double-blind study, funded in its initial phase by supplemental funds granted by the Department of Pediatrics, researchers will enroll 38 autistic children ages 3 to 9. They will look at the influence of gluten and milk proteins in the intestinal function. Gluten is a protein in wheat; casein and whey are proteins in milk. Casomorphin, a peptide in milk; and gliadomorphin, a peptide in gluten, are thought to be related to changes in behavior in these children. Children will be taken off gluten and dairy products before the four-week study and then half will be given gluten/milk powder and half will be given a placebo powder.

Researchers will study intestinal permeability (leaky gut) through urine collection and behavior through psychometric testing.

Co-investigators for the study are J. Marc Rhoads, M.D., professor and director of gastroenterology at the medical school, and Deborah A. Pearson, Ph.D., professor of psychiatry and behavioral sciences.

Children will be enrolled through the UT Physicians pediatric gastroenterology clinic and The University of Texas Mental Sciences Institute. Navarro and Rhoads are attending physicians at Memorial Hermann hospitals. For more information on the study, call 713-500-5669.

Source: General

Autism Recovery Story: Evan

Recovery_storiesPresented By Generation Rescue

My son was diagnosed with ASD in July 2006 at the age of 4. He had always been called “quirky” by his pre-school teachers, but I knew in my heart that there was much more to his tantrums, speech delay, behaviors and massive gut issues than was being addressed.

So, the official diagnosis came of no real surprise. However, hearing the word “autism” sent a jolt through my soul that empowered me to get busy doing everything and anything I could to help my sweet, darling boy.

Immediately, we began with the traditional modalities: ABA, speech and occupational therapy. Slowly, I began to engulf myself in research. Thank Heaven for the internet! I enrolled him in a social skills group at the local University, a swim therapy group with his ST and OT; I started my own social skills program for other families with ASD children; but he was still struggling for control of himself.

So, I began reading about the integrative approach and the DAN! protocol. I just knew that this was our answer. I found an integrative pediatrician to supervise my GF/CF diet. We immediately began a mutli-vitamin, probiotic, L-Carnosine and DHA. Within three months, it was like I had a totally different child. He could have a conversation! He began to engage others in play rather than just parallel play. He was not fixated on certain toys. (His happened to be Thomas the Train). He became potty trained and was having more normal BM’s.

The true testament to my son’s recovery was my husband’s return from a four month military deployment. I began the diet and intervention when my husband left. When we picked my husband up at the airport, he tearfully shared, “I finally have my little boy”. It was the most dramatic thing he’d ever seen.

Prior to his witnessing it, he didn’t really believe that it would work, but he stands by the diet and supplements as the tools that turned our son around.

My son no longer meets the diagnostic criteria for autism; and we are ecstatic to share our story through our support group (and everywhere else) of our success. I diligently seek to help others initiate their GF/CF programs, eliminate toxins from their diet, as this is a massive undertaking; but it is SO worth the effort.

And so to my beautiful and special son, Evan, I say—shine on my love, shine on!

Kelli
Mother of Evan, age 6
Previously diagnosed with Autism

Source: toxins

Autism Understanding Furthered By International Genetic Study

Autism understanding begins when a person realizes that autism is a disorder that affects people differently.  Although autism affects the normal functioning of a person’s perception, attention and thoughts, autism is not characterized by one type of perception, attention and thought.   Instead, it covers a broad spectrum of disorders that may be mild or severe.   Due to the fact that autism is such a complex disorder, medical research is still in the process of understanding how it develops and why it affects certain individuals.

One particular medical project with the aim to find better autism understanding by identifying the gene that causes autism, is the 5 year Autism Genome Project (AGP).  So far, phase I of the AGP has identified a gene and parts of a chromosome to be linked with the occurrence of autism.  The findings of this particular autism study was published online in the Nature Genetics February 18, 2007 issue.

The Autism Genome Project is a global research consortium that is funded by Autism Speaks and the National Institute of Health.  Autism Speaks is a non-profit organization that is dedicated to raising the awareness of autism and raising funds to help research it.

The AGP involves more than 120 scientists from 50 institutions in 19 countries around the world.  The researchers who have collaborated on the project combined their autism expertise, and shared all of the data and samples they had to help identify autism-related genes.

As was mentioned, phase I of this project began 5 years ago in 2002, and it allowed the team of medical experts to gain autism understanding by identifying a single specific gene known as neurexil 1, and part of chromosome 11 which could likely be the cause of autism in children.  These findings are based on the largest autism genome scan that has ever been done.

Scientists have known for many years that autism is a genetic disorder, but only until the AGP have they been able to use special “gene chip” technology to search for genetic similarities in autistics.  Genetic similarities were found in practically all of the autistic individuals within each of the twelve hundred families that that were made part of the project.  The scientists also checked the DNA of each family to look for copy number variations that are believed might be connected to autism and similar disorders.

What the researches discovered in their study was that one particular gene known as neurexin 1 plays a significant role with glutamate; a neurotransmitter that has been formerly linked to autism. Researchers also uncovered an area of chromosome 11 that is suspected to contain a gene that may be involved in the occurrence of autism.   However, this particular gene in chromosome 11 has yet to be identified which is required for further autism understanding.

Based on previous research, and the research that has been uncovered by the study so far, scientists speculate that there may be as many as 6 main genes and 30 additional genes linked to autism.  However, these numbers are only theories, as scientists point out that the actual number of genes could exceed their theory.  Nevertheless, despite the number of genes that may be involved, researchers admit that it is still far too early to dictate how these genes may be responsible for autism.

Currently, phase II of the Autism Genome Project has been announced.  The promising discoveries found in phase I makes scientists hopeful that discovering the genes that cause autism will provide new steps toward autism understanding.  With greater understanding, more effective methods of diagnosis, preventing and treating the disorder can be taken.

Article Source: http://www.articlesbase.com/health-articles/autism-understanding-furthered-by-international-genetic-study-118074.html

About the Author:
By Rachel Evans. Sign up for a free newsletter and discover more about  understanding autism .

Autism and NIDS Treatments - Selective Serotonin Reuptake Inhibitors (SSRI’s)

The only medical agent out there that’s routinely available and directly seems to help the temporal lobe are called the SSRIs, Selective Serotonin Reuptake Inhibitors. The drugs that come under this category are Prozac, Paxil and Zoloft. What these drugs do is, for the first time, work on a specific pathway in the brain. They block the reuptake of the serotonin released.

If the serotonin released “stays around longer / more effectively,” part of the brain works better. Prozac may also alter part of the “neuro-immune” axis, working to increase blood flow and function in the temporal lobe. This increased blood flow and improved function of the temporal lobes, helps many behavioral and processing problems in these “autistic” children. By helping restore and preserve temporal lobe function, one may be helping maintain a healthier brain.

Importantly, this is not an effort to control the children with medicine. A very small dose, usually 2-4 mg, is used with a four or five year old. If controlling a child’s behavior was the goal, a dose of 10 - 20 mg would be used. Instead all that is needed to help function in the brain is a very small (but consistent) dose.

The purpose of using these drugs is an effort to get a child’s brain to work better. In the past, if you talked about an antidepressant you were thinking Valium, Librium, Phenobarbital, that’s how you “calmed” someone down. That’s not what you’re doing with Prozac, Paxil or Zoloft.

Pharmaceutical companies are trying to design drugs that will help the brain more physiologically than the agents out there did before. SSRI’s represent the first of new “designer” drugs, with the capability of acting physiologically within the brain.

These drugs can help a child medically to function better. They help transmitter effect and likely increase blood flow to the area of the brain that was not functioning properly before. And if the brain starts working, the results with these children can be phenomenal. These children are usually extremely bright. (Note: While capable of helping medically, this author believes strongly that one cannot judge their positive effects, avoiding negatives at low dosages, without controlling / combining diet and other steps at the same time.)

Michael J. Goldberg M.D., F.A.A.P.
Avalar Medical Group, Inc.
5620 Wilbur Avenue, Suite 318
Tarzana, Claifornia 91356
Telephone (818) 343-1010
Fax (818) 343-6585

Pediatrics & Young Adults
ADHD/ADD-Learning Disabilities,
Immune Dysfunction Autism

Source: adhd

Immune Modulating Agents for Autism and NIDS

There are agents that have already been tested and developed, and are now undergoing new usage’s testing in adults that will let us adjust the immune system. Hopefully, they will have the ability to fine tune the body and put the immune system back on track. These drugs are already in existence, but are available only through appropriate research protocols. They could potentially correct all of the processing problems associated with autism (and possibly other childhood learning disorders) where “immune-mediated.”

The trouble is, children are the last in line. Even though trials are now starting for adults, no agency wants to test children. The liability is too much. It is only after you’ve proven things extensively in adults that treatment for a child is even considered. If medicine follows its usual course of action, trials for children would be at least another four or five years away.

That is too long to wait. We must find a way to make this happen sooner. Even if the agents are identified that will “normalize” function or stop abnormalities from occurring in autistic children, these agents must be used before children pass important functional and developmental steps that might not be regained if these agents are administered later in life. Funding for this research is of the utmost importance. We can not lose children to autism, who have the potential to lead a normal life.

Even in older children, it appears parts of the brain can be helped significantly. If cognitive function improves, the “equation” for the future changes. But, educators, therapists must start thinking “rehabilitation” rather than just “training.” Often it is extremely slow and difficult to sort out compounding behavioral issues ( perhaps after so many years of being bright but frustrated and dysfunctional secondary to the non-working parts of the brain).

Michael J. Goldberg M.D., F.A.A.P.
Avalar Medical Group, Inc.
5620 Wilbur Avenue, Suite 318
Tarzana, Claifornia 91356
Telephone (818) 343-1010
Fax (818) 343-6585

Pediatrics & Young Adults
ADHD/ADD-Learning Disabilities,
Immune Dysfunction Autism

Source: autism

A New Definition for Autism

Autism as classically defined was and is a devastating disorder. It was a severely incapacitating disability that was relatively rare. It occurred in approximately 1-2 infants per 10,000 births.

In this severe form of “Classic Autism” effective speech was absent. It could include symptoms of repetitive, highly unusual, aggressive and self-injurious behavior. Those afflicted had extremely abnormal ways of relating to people, objects, or events. Parents noticed that something was “not right” generally within the first three to six months of life. These children did not coo or smile. They resisted affection and did not interact normally.

In the last decade, another type of autism has surfaced that is often referred to as “Autistic Syndrome.” Children suffering from this disorder generally appear normal in the first 15-18 months of life. They do not present signs or symptoms pediatricians or neurologists would find atypical. These children create an inconsistency with previous held beliefs that 70-80% of autistic children are mentally retarded. They crawl, sit up, walk, and usually hit normal motor milestones on schedule. Up until the age of onset, they are affectionate and appear to have above average intelligence.

Children with this autistic syndrome may begin to develop some speech but then, without warning, cease to progress, or begin to regress. Suddenly, these children become withdrawn. They are quiet sometimes and hyper at other times. Often self-stimulatory behaviors (i.e. arm flapping, rocking, spinning, or head banging) develop. In time, some manifest symptoms that are both similar and atypical to children previously diagnosed as “classically autistic. “

While training as a pediatrician, I was told if I saw one autistic child in a lifetime of practice it would be one too many. What I am seeing today is not the autism I learned about in medical school twenty years ago. What was once a relatively rare disorder is now twenty times more likely to occur. Before, “autism” was 1-2 per 10,000 births. Now, current statistics suggest a frequency of 20 per 10,000 births (rates of 40 per 10,000 or higher have been suggested).

In the past, autism was considered a “psychiatric” disorder. We now know that autism is a medical condition, not a mental disorder. Perhaps one of the reasons no one has come up with an answer for autism is the way we have thought of it (or rather did not think of it in medicine).

Most “MD” researchers did not look for the answers to autism because they felt this was a disorder that was untreatable medically. Treatment for this affliction was primarily left in the hands of psychologists and a few psychiatrists.

“Autistic syndrome,” though still treated mainly by psychologists and psychiatrists, is also no longer considered a psychiatric disorder. It is a biological disorder that requires medical intervention. Physicians are now just beginning to understand the medical origins as well as the actual and potential treatments for autism.

Even though I believe children with classic autism might be helped medically as our knowledge of the brain’s physiology expands, for now it might be helpful to separate children afflicted with autistic syndrome from those with classic autism. As children with autistic syndrome increasingly become categorized as a “medical” problem, separating them from the many negative connotations and hopelessness associated with “classic” autism could be advantageous to promoting research and funding to help these children. The differences between the two groups may be summarized as follows:

Classic Autism
Generally “abnormal” early (i.e. 3 - 6 months of age)
“Classic” Autistic symptoms / presentation
Presumed “static,” / unchangeable


Autistic Syndrome
An increasing population of children with “Autistic/ PDD” behavioral characteristics
Current estimate 20-40 children / 10,000 (incidence may be as high as 1-5% of Does NOT have “objective” physical signs of neurologic damage / injury Majority (?? All) are immune mediated, appropriately looked upon as a medical dysfunction - open to potential medical therapyGenerally “normal” early (usually until 15 - 18 months of age) Atypical symptoms Asperger’s Landau Kleffner’s ADHD / ADD variants

A potentially progressive disorder (if not treated / corrected) May explain the origin of many cases of “Landau-Kleffner” syndrome.
Autism and the Immune System
I have been in clinical practice for the last twenty years. When my wife developed an “unknown” chronic illness in 1982, I began to explore and research neuro-cognitive dysfunction and immune dysfunction / dysregulation in an effort to help my wife. Eventually she was diagnosed with Chronic Fatigue Syndrome, to what is now CFIDS (Chronic Fatigue Immune Dysfunction Syndrome).

The first suspicion I had that autism might be immune-related occurred in 1985. I was in the middle of exploring various alternative therapies in hopes of helping my wife and others afflicted with CFIDS. About the same time, some autistic children were referred to me for evaluation. These children had never had any blood work-ups because no one thought of their “problem” as a medical one. Much to my surprise, they had similar profiles on amino acid scr ns as the adults I
was seeing with CFIDS. I couldn’t help but wonder “What did Autism have to do with the immune system?”

Michael J. Goldberg M.D., F.A.A.P.
Avalar Medical Group, Inc.
5620 Wilbur Avenue, Suite 318
Tarzana, Claifornia 91356
Telephone (818) 343-1010
Fax (818) 343-6585

Pediatrics & Young Adults
ADHD/ADD-Learning Disabilities,
Immune Dysfunction Autism

Source: treatments

Medical Treatments for Autism and NIDS

Most of the children I see have healthy bodies with reactive and volatile immune systems. The first step, is to check functioning of various systems in the body. Unless another “medical” problem is found, the immune system is what is creating the misbalance / dysfunction in the brain.

Unfortunately, new, potentially safe immune modulators (steroids, IVGG, are old immune modulators, neither generally safe or effective with this type of immune disorder) are not yet available. Until these immune modulating drugs are scientifically tested in controlled studies, the way to help these children must focus on an overall approach using efforts / steps and medicines available now. By the time a child is referred to my office, their immune systems have not been functioning well for a very long time. This dysfunctional process did not occur overnight and it takes time to “cool” down / help “normalize” the body and the immune system.

The closer you can bring the body towards normal, the better the chance that the body may shut off this reactive and dysfunctional immune system. It is a difficult and complicated process to make the body heal itself especially after years of dysfunction. But if you remove some of the “offenders” that cause the immune system to fire when it shouldn’t, you’re making it easier for the body to normalize.

Michael J. Goldberg M.D., F.A.A.P.
Avalar Medical Group, Inc.
5620 Wilbur Avenue, Suite 318
Tarzana, Claifornia 91356
Telephone (818) 343-1010
Fax (818) 343-6585

Pediatrics & Young Adults
ADHD/ADD-Learning Disabilities,
Immune Dysfunction Autism

Source: immune

Autism Treatments - The Role of Allergens and Diet

I usually begin by testing the blood to determine allergies that could possibly trigger the immune system to react. Often autistic children come up allergic to a large number of foods, not necessarily because they are actually allergic, but rather because their immune systems are so “revved-up,” they react to everything.

This reaction may or may not occur as a traditional allergic reaction of asthma, a rash or hives. But what does occur is an immune mediated, abnormal “shut down” of blood flow in the brain that affect the language and social skills area of the brain and central nervous system function.

I generally start to improve the immune system by placing the patient on a diet free from dairy products, chocolate, and whole wheat. The reason for this is to help reduce the stress on the immune system. If dairy, chocolate and whole wheat are taken away, 96 - 98% of probable “food” allergies are alleviated. However, I do not believe that you can correct this condition by diet alone. If this were possible, parents (and physicians) by now, would have heard of multiple, “unbelievable” successes over the years. Reputable “institutions” would be conducting clinical trials to investigate the “successes.”

Since nutritional therapies have not resulted in cures, or even published reports of significantly improved cognitive function, it is illogical, in fact potentially detrimental, to put these children on extreme diets. However, sometimes these children put themselves on extreme diets by only eating a limited number of foods. I don’t think there are a lot of normal children who would be healthy on some of the diets these kids put themselves on.

For most of the children, all that is necessary is to eliminate the “main offenders” in their diets that will cause the immune system to react. It is not necessary to eliminate all wheat. Some doctors and homeopaths recommend the elimination of all gluten and wheat. I think these children show improvement because when they are put on a gluten / wheat free diet, they no longer eat whole wheat. Usually, all that is really needed is to eliminate whole wheat and other whole grains (due to allergenic potential) from the diet.

I do not normally focus on casein beyond eliminating the primary milk products. Because even though they may, in theory, play a slight role in the background, if the allergies overall are lowered, it will decrease the immune system firing off.

It does not matter if “allowed” processed products are used, as long as they do not appear to be a “trigger.” But, avoiding the “main” offenders is extremely important. Eliminating too many products from a child’s diet, increases the risk of disturbing a child’s metabolic balance, rather than helping to normalize it. (Note: Many supplements meant to compensate for the diet extremes, may in themselves have allergenic components, acting as negatives triggers to the immune system and the child overall. They may fail to be properly absorbed or contain dangerous impurities. Children may be at far greater risk from diet and “supplements” than any perceived risk from properly used pharmaceuticals.)

The G.I. tract is loaded with lymphocytes (white blood cells that fight infection and disease).Those lymphocytes communicate with the brain. What has always made sense and is “logical” is if the body is sensitive to milk protein and whole wheat protein, coming into the G.I. tract it could cause the immune system to fire.

As research evolved, it was found that milk and dairy can actually cause a microscopic blood loss in the intestine by a “reactive” inflammation of the bowel. It is interesting to note that most of the world’s populations get violently ill when given cow’s milk. Apparently, it’s not a normal human trait to digest the cow’s milk proteins.

Asian people have much healthier arteries than we do. One of the major assumptions for this is that they eat soy protein instead of dairy protein. Dairy is the number one source of cholesterol. The entire family can be helped indirectly if milk is eliminated from the meals. Parents often worry if their child is getting enough calcium. Soy and rice milk often have calcium and vitamins A and D added. However, if a child (girl or a boy) is eating a normal diet, they will get enough calcium.

In the teenage years, girl’s diets should be supplemented, if you’re not giving them a lot of dairy. But usually, this is not necessary in these first three or four months. As time goes on a calcium supplement may need to be added. Often I will suggest Tums®. Tums® are a very safe source of calcium for a child and they taste good. Inter-related is the fact that many children and adults who are sensitive to milk but still continue to drink milk products, often have iron stores that are low. Their Hgb. / Hct. are chronically on the low side of normal, even if they were not truly “anemic.” This is typically because of a microscopic blood loss occurring through this “inflamed” mucosa. If dairy and milk were eliminated from the diet, and then a biopsy of the intestine was done, the mucosa(the mucous membrane that lines a structure e.g. mouth and lips) would look normal. If milk and dairy were then reintroduced, the mucosa would look raw and inflamed. (Therefore, in approaching the idea of “leaky” gut, helping the body by removing negatives, is more important than “supplements” and nutritional “fixes.”)

As a pediatrician it has been fairly routine for me to see a child do well on formula (even a cow’s milk based one) for 12 months, but when the child is switched to real milk, the child experiences congestion, stuffiness, upset stomach, and a whole realm of symptoms not seen before. Whole protein, unprocessed food is much more allergenic and has a higher incidence of causing the immune system to react.

The truth is, there is not as bad an allergic reaction out of a processed product. When a food is processed, the protein structure is changed. So a child that might go berserk on milk… may not have a reaction to “processed” cheese. When the protein structure is changed, the food will not give as large an allergenic reaction.

Products from the health food stores are not necessarily the best for autistic children because they are less processed and more pure. They have a lot of whole wheat and grains. For these kids, the cheapest white bread (without milk, whole wheat, or whey) is often the best choice.

To illustrate how peculiar the immune system is, when parents seen the results of the food test come back, a routine phone call is, “How come you did not say ‘no eggs’?” You’ll almost always see egg white and egg yolk with very high numbers, and yet I will usually say “ignore it.” The reason being, unless a child has eczema where yolk or egg are triggering off a skin reaction, for some reason the immune pathway fired off by eggs doesn’t seem to play a role in what we are talking about in the brain. I rarely have to worry about taking a child off of eggs, even though you may have this “huge reaction” on the food “screen.” This illustrates how parents need to become aware of what doctors have known and “fought” about for years, there is no “perfect” food test / screen, results must always be interpreted in their clinical context. Too often, parents are being “guided” by interpretation of food and metabolic screens that do not have the capability to do what the parents wish. Many mistakes are potential being made, that may be “metabolically” and physiologically hurting these children.

Although processed food might give a lesser reaction, the importance of avoiding allergens cannot be stressed enough. In the beginning, it is especially important to avoid foods that might trigger the immune system. If the immune system is triggered, the body is affected for a minimum of a week to ten days (or longer). So it’s necessary to be particularly strict at the start of the treatment, when the goal is to cool down the immune system.

If it comes down to choosing a food (cheat) with milk or sugar, choose the sugar. From the sugar the child may get hyper for a few hours, but it wears out of their body relatively quickly. From milk protein or other allergens, the immune system can be affected for up to two - three weeks. However since sugar feeds yeast, it is a good practice to minimize sugars in general.

It is also important to encourage the children to eat more protein. This will help balance out their own amino acids, which in turn will help alleviate some of their problems. All these children need protein. It is also necessary to restrict the starches. Healthy breakfasts, lunches and dinners should be served.

Sometimes this process of restoring the immune system to normal can be very deceptive. The child is doing extremely well, and appears almost well or “cured” to a parent, when everything suddenly falls apart.

A child may appear to be well, but unless the body has shut off this process, they still have a reactive, volatile immune system in the background. Even if a child is functioning at a extremely high level, a child should not be regarded as “cured”, unless the immune system has truly returned to normal.

While a few rare children will actually outgrow this process, especially if you have taken steps to help normalize their bodies; realistically, it will probably take the advent and usage of new drugs that are immune modulators, to truly shut-off their dysregulated immune system.

This treatment needs to be thought of on a continuum. The closer the child gets to normal, the better the chance that the body may shut off this process. But unless you’ve gone that last little step, unless this process shuts off, it must be assumed that the immune system is still volatile and potentially reactive.

The only principle I have continued to find logical over the years, is the idea that I’m trying to just help a child “normalize” their body (and brain). Can I help them balance out their body? If I can change the diet, their own body can help balance itself. There continues to be no evidence in these children of any pre-existing, built-in enzyme or metabolic defect. Therefore, by focusing on the overall intake, encouraging more protein, less starch, a child’s body will help balance out and replace needed amino acids ( the building blocks of the body) and other nutrients.

With rare exceptions, I will never say don’t do something if you truly see a child do better and it’s safe, but in most cases I have found that you can get to the right point if you just think of it as cool down the body’s immune system, help “safely” where medically and nutritionally possible, and extremely important, avoid offenders or triggers. If a child is doing better and their allergy test said they were not allergic to apple, but you give them a drink of apple juice and the child is bouncing off the walls, it doesn’t matter what the test said, that child should not have apple juice. And this is the way parents have to work with their own child.

Until new immune modulators are tested and ready for use with patients, I regard each step of treatment as an attempt to help “cool-down” the immune system, and help the body “adjust” itself in a healthier manner. While the principles are becoming very consistent, each child (his/her body and brain) must be “individualized.”

Michael J. Goldberg M.D., F.A.A.P.
Avalar Medical Group, Inc.
5620 Wilbur Avenue, Suite 318
Tarzana, Claifornia 91356
Telephone (818) 343-1010
Fax (818) 343-6585

Pediatrics & Young Adults
ADHD/ADD-Learning Disabilities,
Immune Dysfunction Autism

Source: allergens

Autism and NIDS - Controlling Candida and Yeast

While taking the risk of opening a medical controversy, this author certainly believes there is a logical connection between yeast and a dysfunctional immune system. However, this theory is not yet widely accepted by the medical community, but over the last few years has become easier to talk about and “discuss”. Candida is a yeast-like fungus that is present in all our bodies. Presumably, yeast / Candida is in every normal G.I. tract. That is where the confusion begins.

Normally, a healthy immune system keeps the yeast in check. If the immune system is not working properly, the yeast have a chance to overgrow and become a problem. Yeast is one of the likely pathogens contributing to a metabolic imbalance that is a secondary result of a dysfunctional / dysregulated immune system. It is NOT the primary reason or cause for autism.

There is logic in saying that if an immune system is dysregulated, a secondary problem potentially due to Candida needs to be treated. Some doctors hypothesize that autism is caused by a “leaky gut.” With this theory comes the assumptions that withdrawing allergens and treating a yeast overgrowth, will help the GI tract to return toward normal. The problem with this thinking is that if yeast is not the cause of autism or PDD, then treating Candida is not going to end the autistic or PDD state. I believe it is only one of the many steps needed to help normalize the body.

Many children afflicted with autism have had frequent ear infections as young children and have taken excessive amounts of antibiotics. This has exasperated the yeast problem in these children. Other possible contributors to Candida overgrowth are hormonal treatments (i.e. steroids, BCP pills, ?? secondary exposure), immunosuppresant drug therapy, exposure to herpes, chicken pox, or other “chronic” viruses, or exposure to chemicals that might upset the immune system. There is an increased probability, that a “general” environmental factor affecting our immune systems (i.e. ozone layer depletion, “toxic” chemicals, etc.) may be operative, affecting many children and adults.

Because it is impossible and not practical to expect anyone to stay on a totally yeast-free diet, ongoing medication, anti-fungal supplements, and avoidance of dietary negatives are necessary to control Candida. Even with the use of anti-fungal drugs, it is still important to limit sugar when there is a yeast problem, because yeast grows 200 times faster in the presence of sugar.

If a potent anti-fungal such as Diflucan or Nizoral is used, it can be assumed that within 1 - 2 months most all of the yeast will die off. I do not use Nilstat or Nystatin. For most children Nystatin is ineffective. And yeast, like bacteria with antibiotics, have become resistant to Nilstat (and other antifungals).

Usually, I will use Nizoral or Diflucan for about four to six months while trying to alleviate other stresses on the immune system and “maximize” a child’s function. In 7- 12 days some patients experience “die off.” This is the only time, a “negative” reaction to a medication can be a good sign.

When the yeast is being killed one experiences either a “sensitization” reaction to “products” of the yeast being killed, or there is release of “formaldehyde” like products or other potentially toxic derivatives, that can contribute to negative symptoms in a patient, including bouncing off the walls, miserable, and irritated. I know it is ironic, because it actually is a good sign that the child has a yeast problem that can be corrected with medication.

It is important that the parents check in during “die-off” so I can be sure what is occurring is indeed die-off and not a reaction to the medication. Die-off usually lasts about 7-14 days and after that time the change in the child can be rather dramatic. If the die-off does not end in 14 - 17 days, it is generally a reason to change choice of anti-fungal.

If the treatment is successful, usually eye-contact improves. The children seem more tuned in and less “foggy.” Parents report that after the yeast is under control the frequency of inappropriate noises, teeth grinding, biting, hitting, hyperness, and aggressive behavior decrease. The children no longer act almost drunk by being silly and laughing inappropriately.

While on Nizoral or Diflucan, I have the patient take monthly blood tests to monitor liver function before any damage might occur. I tend to be on the cautious side, “officially” testing is recommended every 2 - 3 months.

I change medication at six months, though in theory one could go longer. The reason I stop at six months is because Nizoral has a very mild effect on the adrenocortical axis. It’s part of the internal steroid mechanism. While this may even be part of how “Nizoral” helps the body, it also limits how long one should be on Nizoral. Generally, I will try to switch to Amphotericin B, which has recently been licensed as an oral liquid in this country, can now be legally compounded by certain pharmacies in the U.S.

If the antifungal therapy is stopped completely, and the body’s immune system has not returned to normal, the yeast will return. Ultimately, the key is the body’s own ability to keep in check an organism that it doesn’t want to have there to start with.

Some doctors mistakenly give medication to control the yeast for only a few weeks or even a month. Then the treatment is stopped because the child is doing better. The problem with this kind of therapy is that if a child is helped for a short time and then the treatment is withdrawn, the yeast is going to come back, perhaps even as a stronger, more resistant strain. Whereas if the treatment took that child to normal, and their immune system became normal, it would be possible to withdraw all treatment and the child would remain healthy.

Michael J. Goldberg M.D., F.A.A.P.
Avalar Medical Group, Inc.
5620 Wilbur Avenue, Suite 318
Tarzana, Claifornia 91356
Telephone (818) 343-1010
Fax (818) 343-6585

Pediatrics & Young Adults
ADHD/ADD-Learning Disabilities,
Immune Dysfunction Autism

Source: General

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